Full Publication List

27) Xia W, Morcom L, Xu Z, Lu IL, Wang Q, Hoi KK, Wei M, Zhu K, Jordan G, Tang X, Gonzalez Maya J, Mattera V, Panigrahi S, Kawaguchi R, Emery B, Franco SJ, Geschwind D, Popko B, Rowitch DH, Fancy SPJ. Expansion of outer cortical Cux2 neurons requires adaptations for DNA repair.

Nature (2026)

26) Morcom L, Xia W, Xu Z, Awasthi Y, Geywitz C, Ellis MO, Noli T, Zulji A, Yamamoto D, Girdler GC, Kai L, Zhu K, Wei M, Tang XY, Hoi KK, Gonzalez Maya J, Duncan GJ, Vaquie AM, Gold Diaz D, Kawaguchi R, Liu E, Sun Y, Yang D, Jordan G, Lu IL, Holmqvist S, Bartels T, Ridley K, Choi JJ, Franco SJ, Huang EJ, Emery B, Geschwind D, Schirmer L, Balmus G, Popko B, Fancy SPJ, Rowitch DH. DNA damage burden causes selective CUX2 neuron loss in neuroinflammation.

Nature (2026)

25) Zhu K, Liu Y, Min J-H, Joshua V, Lin J, Li Y, Kreutzmann J.C., Guo Y, Xia W, Mohammadi E, Pieber M, Suerth V, Xia Y, Andrusivova Z, Hugnot J-P, Kanatani S, Ulhén P, Lundeberg J, Li X, Fancy SPJ, Sarlus H, Harris RA, Lund H. TGFβ signaling mediates microglial resilience to spatiotemporally restricted myelin degeneration.

Nature Neuroscience (2026)

24) Benito-Cuesta I, Min JH, Guo Y, Adriana Virgilio G, Suerth V, Bencina S, Trigo-Alonso P, Zhu K, Pahlevan Kakhki M, Sarlus H, Harris RA. Allogeneic MHC-mismatched microglia-like cell replacement as a therapeutic approach for multiple sclerosis.

Journal of Neuroinflammation (2026)

23) Sarlus H, Guo Y, Bencina S, Zhu K, Joshua V, Adriana Virgilio G, Cheng Y, Lin J, Min JH, Benito-Cuesta I, Suerth V, Trigo-Alonso P, Thomas O, Rykaczewska U, Guerreiro Cacais AO, Jagodic M, Gramignoli R, Harris RA.

BioRxiv (2025)

22) Wang D, Zhang T, Shao Q, Wu X, Zhao X, Zhang H, Wang Y, Sun J, Chang X, Zhu K, Wu S, Cao L, Chen W, Wang J. GSDME-mediated pyroptosis in microglia exacerbates demyelination and neuroinflammation in multiple sclerosis: insights from humans and cuprizone-induced demyelination model mice.

Cell Death & Differentiation (2025)

21) Wang Y, Baars I, Berzina I, Rocamonde-Lago I, Shen B, Yang Y, Lolaico M, Waldvogel J, Smyrlaki I, Zhu K, Harris R, Högberg B. A DNA Robotic Switch with Regulated Autonomous Display of Cytotoxic Ligand Nanopatterns.

Nature Nanotechnology (2024)

20) Wang D, Wang X, Li S, Zhang T, Yang Y, Wang Y, Zhao X, Li K, Wang YQ, Li Y, Zhu K#, Wang J#. Sanguinarine modulates microglial function via PPARγ activation and protects against CNS demyelination.

International Immunopharmacology (2024)

19) Lund H, Hunt M, Kurtovic Z, Sandor K, Fereydouni N, Julien A, Göritz C, Han J, Zhu K, Harris RA, Lampa J, Haglund L, Yaksh TL, Svensson CI. A network of CD163+ macrophages monitors enhanced permeability at the blood-dorsal root ganglion barrier.

Journal of Experimental Medicine (2023)

18) Zhang J, Koolmeister C, Han J, Filograna R, Hanke L, Àdori M, Sheward DJ, Teifel S, Gopalakrishna S, Shao Q, Liu Y, Zhu K, Harris RA, Mclnerney G, Murrell B, Aoun M, Bäckdahl L, Holmdahl R, Pekalski M, Wednell A, Engvall M, Wredenberg A, Karlsson Hedestam GB, Castro Dopico X, Rorbach J. Antigen receptor stimulation induces purifying selection against pathogenic mitochondrial tRNA mutations.

JCI Insight (2023)

17) Sun J*, Zhu K*, Wang Y*, Wang D, Zhang M, Sarlus H, Benito-Cuesta I, Zhao X, Zou Z, Zhong Q, Feng Y, Wu S, Wang Y, Harris RA, Wang J. Activation of TRPV1 receptor facilitates myelin repair following demyelination via the regulation of microglial function (COVER STORY).

Acta Pharmacologica Sinica (2023)

16) Wang Y, Sun J, Zhu K, Wang D, Zhao X, Zhang H, Wu S, Wang Y, Wang J. Microglial aryl hydrocarbon receptor enhances phagocytic function via SYK and promotes remyelination in the cuprizone mouse model of demyelination.

Journal of Neuroinflammation (2023)

15) Zhu K, Wang Y, Sarlus H, Geng K, Nutma E, Sun J, Kung S, Bay C, Han J, Benito-Cuesta I, Lund H, Amor S, Wang J, Zhang XM, Kutter C, Guerreiro Cacais A.O., Högberg B, Harris RA. Myeloid cell-specific topoisomerase 1 inhibition using DNA origami mitigates neuroinflammation.

EMBO Reports (2022)

14) Zhou K, Han J, Lund H, Boggavarapu N, Lauschke V, Goto S, Cheng H, Wang Y, Tachi A, Xie C, Zhu K, Sun Y, Osman A, Liang D, Han W, Gemzell-Danielsson K, Betsholtz C, Zhang XM, Zhu C, Enge M, Joseph B, Harris RA, Blomgren K. An overlooked subset of Cx3cr1wt/wt microglia in the Cx3cr1CreER-Eyfp/wt mouse has a repopulation advantage over Cx3cr1CreER-Eyfp/wt microglia following microglial depletion.

Journal of Neuroinflammation (2022)

13) Ineichen B, Zhu K, Carlström K. Axonal mitochondria adjust in size depending on g-ratio of surrounding myelin during homeostasis and advanced remyelination.

Journal of Neuroscience Research (2021)

12) Rangasami V, Samanta S, Parihar V, Asawa K, Zhu K, Varghese O, Teramura Y, Nilson B, Hilborn J, Harris RA, Oommen O. Harnessing hyaluronic acid-based nanoparticles for combination therapy: A novel approach for suppressing systemic inflammation and to promote antitumor macrophage polarization.

Carbohydrate Polymers (2021)

11) Zou Z, Sun J, Kang Z, Wang Y, Zhao H, Zhu K#, Wang J#. Tyrosine Kinase Receptors Axl and MerTK Mediate the Beneficial Effect of Electroacupuncture in a Cuprizone-Induced Demyelinating Model.

Evidence-Based Complementary and Alternative Medicine (2020)

10) Carlström K, Zhu K, Ewing E, Krabbendam I, Harris RA, Falcão A, Jagodic M, Castelo-Branco G, Piehl F. Gsta4 controls apoptosis of differentiating adult oligodendrocytes during homeostasis and remyelination via the mitochondria-associated Fas-Casp8-Bid-axis.

Nature Communications (2020)

9) Han J, Fan Y, Zhou K, Zhu K, Blomgren K, Lund H, Zhang XM, Harris RA. Underestimated Peripheral Effects Following Pharmacological and Conditional Genetic Microglial Depletion.

International Journal of Molecular Sciences (2020)

8) Han J, Zhu K, Zhou K, Hakim R, Sankavaram S, Blomgren K, Lund H, Zhang XM, Harris RA. Sex-Specific Effects of Microglia-Like Cell Engraftment during Experimental Autoimmune Encephalomyelitis.

International Journal of Molecular Sciences (2020)

7) Zhu K, Pieber M, Han J, Blomgren K, Zhang XM, Harris RA, Lund H. Absence of microglia or presence of peripherally-derived macrophages does not affect tau pathology in young or old hTau mice.

Glia (2020)

6) Chen Y, Sun J, Chen W, Wu G, Wang Y, Zhu K#, Wang J#. miR-124/VAMP3 is a novel therapeutic target for mitigation of surgical trauma-induced microglial activation.

Signal Transduction and Targeted Therapy (2019)

5) Zhu K, Sun J, Kang Z, Zou Z, Wu X, Wang Y, Wu G, Harris RA, Wang J. Repurposing of omeprazole for oligodendrocyte differentiation and remyelination.

Brain Research (2019)

4) Han J, Zhu K, Zhang XM, Harris RA. Enforced microglial depletion and repopulation as a promising strategy for the treatment of neurological disorders (review).

Glia (2019)

3) Lund H, Pieber M, Parsa R, Grommisch D, Ewing E, Kular L, Han J, Zhu K, Nijssen J, Hedlund E, Needhamsen M, Ruhrmann S, Guerreiro-Cacais AO, Berglund R, Forteza MJ, Ketelhuth DFJ, Butovsky O, Jagodic M, Zhang XM, Harris RA. Fatal demyelinating disease is induced by monocyte-derived macrophages in the absence of TGF-β signaling.

Nature Immunology (2018)

2) Lou W, Chen Y, Zhu K, Deng H, Wu T, Wang J. Polyphyllin I Overcomes EMT-Associated Resistance to Erlotinib in Lung Cancer Cells via IL-6/STAT3 Pathway Inhibition.

Biological and Pharmaceutical Bulletin (2017)

1) Zhu K, Sun J, Kang Z, Zou Z, Wu G, Wang J. Electroacupuncture Promotes Remyelination after Cuprizone Treatment by Enhancing Myelin Debris Clearance.

Frontiers in Neuroscience (2017)